Supplement
Research Update
Whey Protein increases Glucose transporters for greater muscle glycogen replenishment
By Veeraj Vic Goyaram
I
am very pleased to report this study because it involves Glucose Transporters
in skeletal muscle, the same molecules that I do research in. In this study, researchers from the
University of Campinas in Sao Paulo showed how whey protein improves glycogen
(stored muscle carbohydrate) replenishment following exercise, allowing
improved recovery. They showed that this happens by improved activity of
glucose transporters named GLUT4 in a rat model which received whey protein
following exercise.
What is GLUT4?
The
main transporter of glucose in muscle is Glucose Transporter 4 (GLUT4). GLUT4
is found inside the cell in the resting state of the cell. After a meal or
after an exercise bout, these GLUT4 molecules move to the surface of the
cell where they take up glucose from the
bloodstream. The fact that exercise can do this is fantastic news for
diabetics and exercising individuals because it means better blood glucose control and muscle glycogen replenishment, respectively. If you need more info on the topic please contact me.
What the researchers did
The
researchers, Morato and colleagues had three groups of rats fed experimental
diets containing (A) Casein, (B) Whey
Protein and (C) Whey protein Hydrolysate. The animals were subjected to exercise
protocol (60min of treadmill running at a speed of 15m/min) and then sacrificed
16 hours later. Their muscles were taken out and analysed.
What was found and what are the implications?
- In rats fed Whey protein and Whey protein hydrolysate, GLUT4 levels on the cell membrane was higher following after exercise compared to rats fed casein.
- This increased level of GLUT4 at the cell surface membrane allowed more glucose to be taken up after exercise for better recovery and the replenishment of muscle glycogen used during exercise.
- This research study shows the importance of taking a whey protein supplement post training although further research is needed in this topic in human athletes and in diabetics because the latter have reduced GLUT4 movement to the cell membrane.
Exercise increased GLUT4 protein levels in the muscle cell membrane in all rats. However, this increase was more pronounced in rats fed whey protein and whey protein hydrolysate than rats fed casein |
Anything you don't understand or want to know more?
Please free to drop me a line on vicgoyaram@gmail.com. Don't go ask the wrong persons.
Reference
Reference
Morato
PN, Lollo PC, Moura CS, Batista TM, Camargo RL, Carneiro EM, Amaya-Farfan J. Whey
protein hydrolysate increases translocation of GLUT-4 to the plasma membrane
independent of insulin in wistar rats. PLoS One. 2013 Aug 30;8(8):e71134.
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CLICK HERE TO BUY. That would be your greatest investment! I am an affiliate of examine.com. If you buy the book I get a little commission. This allows me to bring you more great FREE articles. Science delivered to your doorstep from someone who does the research in the exercise/ nutrition lab, who lifts and understands your needs. |
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